Patrick J. Paddison

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Emily Bernstein et al. · Genes & Development · 2002 · 1.5K citations · Full text

A resource for large-scale RNA-interference-based screens in mammals

Patrick J. Paddison, José M. Silva, Douglas S. Conklin et al. · Nature Cell Biology · 2004 · 686 citations

Genetics, Rna Biology, Transcriptomics Technology +6

Second-generation shRNA libraries covering the mouse and human genomes

José M. Silva, Mamie Z. Li, Ken C. N. Chang et al. · Nature Genetics · 2005 · 617 citations

Second-generation Shrna Libraries, Genetics, Small Rna +5

Wnt and TGF-β signaling are required for the induction of an <i>in vitro</i> model of primitive streak formation using embryonic stem cells

Paul Gadue, Tara L. Huber, Patrick J. Paddison et al. · Proceedings of the National Academy of Sciences · 2006 · 550 citations · Full text

Genetics, Stem Cell Biology, Cell Specialization +21

Stable suppression of gene expression by RNAi in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Gregory J. Hannon · Proceedings of the National Academy of Sciences · 2002 · 549 citations · Full text