Patrick J. Paddison

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Emily Bernstein et al. · Genes & Development · 2002 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +13

A resource for large-scale RNA-interference-based screens in mammals

Patrick J. Paddison, José M. Silva, Douglas S. Conklin et al. · Nature Cell Biology · 2004 · 699 citations

Life Sciences, Genetics, Molecular Biology +8

Second-generation shRNA libraries covering the mouse and human genomes

José M. Silva, Mamie Z. Li, Ken C. N. Chang et al. · Nature Genetics · 2005 · 619 citations

Life Sciences, Genetics, Molecular Biology +8

Wnt and TGF-β signaling are required for the induction of an <i>in vitro</i> model of primitive streak formation using embryonic stem cells

Paul Gadue, Tara L. Huber, Patrick J. Paddison et al. · Proceedings of the National Academy of Sciences · 2006 · 557 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +17

Stable suppression of gene expression by RNAi in mammalian cells

Patrick J. Paddison, Amy A. Caudy, Gregory J. Hannon · Proceedings of the National Academy of Sciences · 2002 · 550 citations · Full text

Life Sciences, Genetics, Molecular Biology +9