B cells engineered to express pathogen-specific antibodies protect against infection

Howell Moffett, Carson K. Harms, Kristin Fitzpatrick, Marti R. Tooley, Jim Boonyaratanakornkit, Justin J. Taylor

Science Immunology · 2019 · 158 citations · 53 references

Concepts

Abstract

-deficient mice. This approach offers the opportunity to achieve sterilizing immunity against pathogens for which traditional vaccination has failed to induce or maintain protective antibody responses.

References

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