Concepedia

B Cell Engineering

B Cell Engineering is a methodological framework within ex vivo gene delivery that involves the precise genetic modification of B lymphocytes to confer novel or enhanced functional properties for therapeutic or research applications.

49

Publications

3.7K

Citations

372

Authors

149

Institutions

Publications per year

2017–2026

20

Parents

Publications

49

Reverse engineering of regulatory networks in human B cells

Katia Basso, Adam A. Margolin, Gustavo Stolovitzky et al. · Nature Genetics · 2005 · 1.4K citations

, , +16

Engineering human hematopoietic stem/progenitor cells to produce a broadly neutralizing anti-HIV antibody after in vitro maturation to human B lymphocytes.

Xin Luo, Emily Maarschalk, Ryan M. O’Connell et al. · Blood · 2008 · 165 citations · Full text

, , +17

B cells engineered to express pathogen-specific antibodies protect against infection

Howell Moffett, Carson K. Harms, Kristin Fitzpatrick et al. · Science Immunology · 2019 · 158 citations

, , +16

Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells

King L. Hung, Iana Meitlis, Malika Hale et al. · Molecular Therapy · 2017 · 148 citations · Full text

, , +15

The high efficiency, human B cell immortalizing heteromyeloma CB-F7

Roland Grunow, Sigbert Jahn, Tomas Portsmann et al. · Journal of Immunological Methods · 1988 · 101 citations

, , +6

1–5 of 49

Authors

372

  1. DH
    Deli Huang

    Scripps Research Institute, United States

    4 publications · 302 citations

    4

    h-index

  2. JE
    James E. Voss

    Scripps Research Institute, United States

    4 publications · 302 citations

    4

    h-index

  3. DN
    David Nemazee

    Scripps Research Institute, United States

    4 publications · 302 citations

    4

    h-index

  4. MT
    Mary Tenuta

    Scripps Research Institute, United States

    3 publications · 201 citations

    3

    h-index

  5. DR
    Dennis R. Burton

    Scripps Research Institute, United States

    3 publications · 207 citations

    3

    h-index

1–5 of 372

Institutions

149

  1. Scripps Research Institute

    San Diego, United States

    5 h-index

    57 publications

    3.5K citations

  2. Universidad Autónoma de Madrid

    Madrid, Spain

    5 h-index

    13 publications

    465 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    33 publications

    967 citations

  4. Ragon Institute of MGH, MIT and Harvard

    Cambridge, United States

    3 h-index

    5 publications

    313 citations

  5. Lomonosov Moscow State University

    Moscow, Russia

    3 h-index

    4 publications

    138 citations

  6. University of Washington

    Seattle, United States

    3 h-index

    6 publications

    505 citations

  7. Ludwig-Maximilians-Universität München

    Munich, Germany

    3 h-index

    19 publications

    1.2K citations

  8. Karolinska Institutet

    Stockholm, Sweden

    3 h-index

    5 publications

    313 citations

1–8 of 149

Venues

  1. Blood

    7 publications · 543 citations

    7

    h-index

  2. Journal of Immunological Methods

    4 publications · 178 citations

    4

    h-index

  3. Gene Therapy

    3 publications · 60 citations

    3

    h-index

  4. Nature Communications

    3 publications · 246 citations

    3

    h-index

  5. Methods in molecular biology

    Book series · 3 publications · 99 citations

    3

    h-index

1–5