Concepedia

Immune Cell Engineering

Immune Cell Engineering is a subfield of cellular engineering and immunotechnology that systematically designs, modifies, and controls immune cells—primarily through genetic, molecular, and biophysical interventions—to alter their phenotype and function for defined research and therapeutic purposes.

855

Publications

54.8K

Citations

6.5K

Authors

1.3K

Institutions

Publications per year

2017–2026

543

Parents

Children

Publications

855

Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

Ye Li, David Hermanson, Branden S. Moriarity et al. · Cell stem cell · 2018 · 988 citations · Full text

, , +10

Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity

E Liu, Yijiu Tong, Gianpietro Dotti et al. · Leukemia · 2017 · 811 citations

, , +16

Targeting cardiac fibrosis with engineered T cells

Haig Aghajanian, Tōru Kimura, Joel G. Rurik et al. · Nature · 2019 · 796 citations · Full text

, , +14

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

T. Deuse, Xiaomeng Hu, Alessia Gravina et al. · Nature Biotechnology · 2019 · 735 citations

, , +12

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors

Kole T. Roybal, Jasper Z. Williams, Leonardo Morsut et al. · Cell · 2016 · 727 citations · Full text

, , +12

1–5 of 855

Authors

6.5K

  1. CH
    Carl H. June

    University of Pennsylvania, United States

    20 publications · 2.7K citations

    18

    h-index

  2. LJ
    Laurence J.N. Cooper

    The University of Texas MD Anderson Cancer Center, United States

    16 publications · 2.7K citations

    15

    h-index

  3. RE
    Richard E. Champlin

    The University of Texas MD Anderson Cancer Center, United States

    16 publications · 3.3K citations

    14

    h-index

  4. DA
    Dean A. Lee

    The University of Texas MD Anderson Cancer Center, United States

    14 publications · 2.4K citations

    13

    h-index

  5. GD
    Gianpietro Dotti

    Baylor College of Medicine, United States

    13 publications · 1.7K citations

    13

    h-index

1–5 of 6.5K

Institutions

1.3K

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    27 h-index

    32 publications

    4.8K citations

  2. University of Pennsylvania

    Philadelphia, United States

    25 h-index

    31 publications

    3.8K citations

  3. Harvard University

    Cambridge, United States

    25 h-index

    33 publications

    2.1K citations

  4. University of California, San Francisco

    San Francisco, United States

    22 h-index

    28 publications

    4.2K citations

  5. Stanford University

    Stanford, United States

    21 h-index

    27 publications

    3.1K citations

  6. Parker Institute for Cancer Immunotherapy

    San Francisco, United States

    20 h-index

    26 publications

    3.3K citations

  7. University of Washington

    Seattle, United States

    20 h-index

    28 publications

    1.8K citations

  8. Inserm

    Paris, France

    20 h-index

    29 publications

    1.5K citations

1–8 of 1.3K

Venues

  1. Molecular Therapy

    45 publications · 3.7K citations

    32

    h-index

  2. Frontiers in Immunology

    39 publications · 2.1K citations

    27

    h-index

  3. The Journal of Immunology

    JI · 27 publications · 2.6K citations

    23

    h-index

  4. Blood

    33 publications · 2K citations

    20

    h-index

  5. Human Gene Therapy

    20 publications · 1.4K citations

    17

    h-index

1–5