Concepedia

Knockdown of hypoxia-inducible factor-1 alpha by tumor targeted delivery of CRISPR/Cas9 system suppressed the metastasis of pancreatic cancer

Man Li, Hanbing Xie, Yingke Liu, Chunyu Xia, Xingli Cun, Yang Long, Xiaoxiao Chen, Miao Deng, Rong Guo, Zhirong Zhang,

Journal of Controlled Release · 2019 · 126 citations · 38 references

DOI

Concepts

References

38

Cancer treatment and survivorship statistics, 2016

Kimberly D. Miller, Rebecca L. Siegel, Chun Chieh Lin et al. · CA A Cancer Journal for Clinicians · 2016 · 6.2K citations · Full text

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DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

, , +10

Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

Stan J. J. Brouns, Matthijs M. Jore, Magnus Lundgren et al. · Science · 2008 · 2.6K citations · Full text

, , +13

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

John A. Zuris, David B. Thompson, Yilai Shu et al. · Nature Biotechnology · 2014 · 1.5K citations · Full text

, , +12

Direct regulation of TWIST by HIF-1α promotes metastasis

Muh Hwa Yang, Min-Zu Wu, Shih Hwa Chiou et al. · Nature Cell Biology · 2008 · 1.3K citations

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