Concepedia

Intrinsic relative potency of a series of pyrrolizidine alkaloids characterized by rate and extent of metabolism

Cathy Lester, John Troutman, Cindy Obringer, Kenneth R. Wehmeyer, Peter Stoffolano, Michael Karb, Yan Xu, Amy L. Roe, G.J. Carr, Karen Blackburn,

Food and Chemical Toxicology · 2019 · 29 citations · 21 references

DOI

Concepts

References

21

Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes

R. Scott Obach · Drug Metabolism and Disposition · 1999 · 1.2K citations

, , +17

Scientific Opinion on Pyrrolizidine alkaloids in food and feed

EFSA Journal · 2011 · 340 citations · Full text

, , +10

Risks for human health related to the presence of pyrrolizidine alkaloids in honey, tea, herbal infusions and food supplements

Helle Katrine Knutsen, Jan Alexander, Lars Barregård et al. · EFSA Journal · 2017 · 240 citations · Full text

, , +17

Metabolic Activation of Pyrrolizidine Alkaloids: Insights into the Structural and Enzymatic Basis

Jianqing Ruan, Mengbi Yang, Peter P. Fu et al. · Chemical Research in Toxicology · 2014 · 153 citations

, , +16

Value of A260/A280 ratios for measurement of purity of nucleic acids.

Manchester Kl · PubMed · 1995 · 114 citations

, , +11