Mengbi Yang

Metabolic Activation of Pyrrolizidine Alkaloids: Insights into the Structural and Enzymatic Basis

Jianqing Ruan, Mengbi Yang, Peter P. Fu et al. · Chemical Research in Toxicology · 2014 · 153 citations

Pharmacy, Pharmacology, Toxicology +16

First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans

Mengbi Yang, Jianqing Ruan, Hong Gao et al. · Archives of Toxicology · 2017 · 83 citations

Medicine, Pharmacology, Hepatology +7

Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity

Mengbi Yang, Jianqing Ruan, Peter P. Fu et al. · Chemico-Biological Interactions · 2015 · 79 citations

Medicine, Pharmacology, Toxicology +15

Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids

Mengbi Yang, Jiang Ma, Jianqing Ruan et al. · Archives of Toxicology · 2019 · 74 citations

Medicine, Pharmacology, Toxicology +16

Efficient brain uptake of piperine and its pharmacokinetics characterization after oral administration

Tianjing Ren, Qianwen Wang, Chenrui Li et al. · Xenobiotica · 2017 · 44 citations

Pharmacy, Pharmacokinetics, Pharmacology +17