An AIE-active theranostic probe for light-up detection of Aβ aggregates and protection of neuronal cells

Abstract

with aggregation-induced emission (AIE) characteristics for light-up detection of Aβ fibrils and plaques, inhibition of Aβ fibrillation, disassembly of preformed Aβ fibrils, and protection of neuronal cells. The AIE-active theranostic probe is thus promising for study of Aβ fibrils and plaques in Alzheimer's disease.