Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress

IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis

Eugene Varfolomeev, John W. Blankenship, Sarah M. Wayson et al. · Cell · 2007 · 1.2K citations · Full text

Inflammation, Cytokine, Induce Autoubiquitination +12

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

Esther A. Obeng, Louise Carlson, Delia Gutman et al. · Blood · 2006 · 1.1K citations · Full text

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

James E. Vince, W. Wei‐Lynn Wong, Nufail Khan et al. · Cell · 2007 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

Simone Fulda, Wolfgang Wick, Michael Weller et al. · Nature Medicine · 2002 · 740 citations

Medicine, Apoptosis, Malignant Glioma +10

The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells.

Simone Fulda, Hauke Sieverts, Claudia Friesen et al. · PubMed · 1997 · 450 citations

Cell Regulation, Medicine, Apoptosis +15