Concepedia

Pharmacokinetic evaluation of medicinally important synthetic N,N′ diindolylmethane glucoside: Improved synthesis and metabolic stability

Asmita Magotra, Abhishek Gour, Deepak K. Sharma, Ashutosh K. Dash, Gurdarshan Singh, Debaraj Mukherjee, Utpal Nandi

Bioorganic & Medicinal Chemistry Letters · 2019 · 11 citations · 23 references

DOI

Concepts

References

23

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Applied Biopharmaceutics and Pharmacokinetics.

Annals of Internal Medicine · 1981 · 1.2K citations

, , +17

Generation of a Set of Simple, Interpretable ADMET Rules of Thumb

M. Paul Gleeson · Journal of Medicinal Chemistry · 2008 · 961 citations

, , +17

Prediction of drug solubility from Monte Carlo simulations

William L. Jorgensen, Erin M. Duffy · Bioorganic & Medicinal Chemistry Letters · 2000 · 368 citations

, , +12

In Situ Kinase Profiling Reveals Functionally Relevant Properties of Native Kinases

Matthew P. Patricelli, Tyzoon Nomanbhoy, Jiangyue Wu et al. · Chemistry & Biology · 2011 · 357 citations

, , +9