Synthesis and biological evaluation of nitroxide labeled pyrimidines as Aurora kinase inhibitors

The PyMOL Molecular Graphics System

Warren L. DeLano · Medical Entomology and Zoology · 2002 · 18.1K citations

Life Sciences, Biology, Computational Biology +11

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore et al. · Nature Medicine · 2004 · 954 citations · Full text

Medicine, Oncology, Pharmacology +13

Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability.

Takahide Ota, Shiho Suto, Hiroshi Katayama et al. · PubMed · 2002 · 293 citations

Life Sciences, Molecular Biology, Oncology +17

Discovery, Synthesis, and <i>in Vivo</i> Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase

Andrew Mortlock, Kevin M. Foote, Nicola M. Heron et al. · Journal of Medicinal Chemistry · 2007 · 274 citations · Full text

Medicine, Oncology, Pharmacology +13

Aurora‐C kinase is a novel chromosomal passenger protein that can complement Aurora‐B kinase function in mitotic cells

Kaori Sasai, Hiroshi Katayama, David L. Stenoien et al. · Cell Motility and the Cytoskeleton · 2004 · 268 citations

Life Sciences, Cell Biology, Molecular Biology +14