Journal of Neurogastroenterology and Motility · 2019 · 32 citations · 34 references
Life SciencesNutritionNutritional SciencesBowel ManagementGastroenterologyMicrobiome ResearchConstipation ManagementFunctional Gastrointestinal DisordersGut MicrobiotaIrritable Bowel SyndromeLactic Acid BacteriaProbioticsBristol Stool Form ScaleLactic Acid Bacteria ProbioticsProbiotic BeveragesProbiotic Effects On Gut MicrobiotaProbiotic PropertiesRome CriteriaStool CharacteristicsStool Form Assessment
BACKGROUND/AIMS: strain Shirota (LcS) on constipation-related symptoms, especially stool consistency, of constipated patients. METHODS: Constipated patients meeting the Rome III criteria were divided into 3 groups according to the Bristol Stool Form Scale (BSFS): hard (hard stool [HS], BSFS ＜ 3), normal (normal stool [NS], ≤ 3 BSFS ≤ 4), and soft (soft stool [SS], 4 ＜ BSFS ≤ 5) stools. Subjects in each group consumed a probiotic beverage containing 10¹⁰ colony-forming units of LcS daily for 28 days. RESULTS: abundance in SS. CONCLUSIONS: LcS supplementation improved the constipation-related symptoms in constipated subjects. Differences in baseline stool consistency could result in different anti-constipation effects of LcS intervention. LcS balanced the stool consistency-softened the HS and hardened the SS. These effects could be associated with modulation of the gut microbiota and SCFA production.
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