Concepedia

Antioxidant-Inspired Drug Discovery: Antitumor Metabolite Is Formed in Situ from a Hydroxycinnamic Acid Derivative upon Free-Radical Scavenging

Laura Fási, Florent Di Meo, Ching‐Ying Kuo, Sonja Stojković Burić, Ana Martins, Norbert Kúsz, Zoltán Béni, Miklós Dékány, György Tibor Balogh, Milica Pešić,

Journal of Medicinal Chemistry · 2019 · 39 citations · 33 references

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Concepts

Abstract

OH radicals. Our results demonstrate the pharmacological value of an in situ-formed, oxidative stress-related metabolite of an antioxidant. This might be of particular importance for designing new strategies for antioxidant-based drug discovery.

References

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