Concepedia

Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination

Hanwen Chen, Hui Lin, Shujun Xie, Bo Huang, Yufeng Qian, Kelie Chen, Yuequn Niu, Han‐Ming Shen, Jianting Cai, Peiwei Li,

Toxicology and Applied Pharmacology · 2018 · 77 citations · 41 references

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41

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.9K citations · Full text

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Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

Franz Bauernfeind, Gábor Horváth, Andrea Stutz et al. · The Journal of Immunology · 2009 · 2.9K citations · Full text

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae et al. · Nature Medicine · 2015 · 2.8K citations · Full text

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.6K citations · Full text

, , +11