Identification of 1,2,4-triazoles as new thymidine phosphorylase inhibitors: Future anti-tumor drugs

Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer

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Thymidine phosphorylase is angiogenic and promotes tumor growth.

Amir Moghaddam, H T Zhang, Tai‐Ping Fan et al. · Proceedings of the National Academy of Sciences · 1995 · 392 citations

Medicine, Molecular Biology, Oncology +14

1,2,3‐Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV‐1 Protease Inhibitors

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Pharmacy, Medicinal Chemistry, Pharmacology +16

A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant

Michael J. Giffin, H. Heaslet, Ashraf Brik et al. · Journal of Medicinal Chemistry · 2008 · 244 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Synthesis, HIV-RT inhibitory activity and SAR of 1-benzyl-1H-1,2,3-triazole derivatives of carbohydrates

Fernando de Carvalho da Silva, Maria Cecília B. V. de Souza, Izabel I.P. Frugulhetti et al. · European Journal of Medicinal Chemistry · 2008 · 234 citations · Full text

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