Concepedia

Publication | Closed Access

Radiation-induced astrocyte senescence is rescued by Δ133p53

DOI

112

Citations

34

References

2019

Year

Casmir Turnquist, Jessica A. Beck, Izumi Horikawa, Ifeyinwa E. Obiorah, Natalia von Muhlinen, Bořivoj Vojtěšek, David P. Lane, Christopher Grunseich, Joeffrey Chahine, Heather M. Ames,
Neuro-Oncology

Abstract

Restoring expression of the endogenous p53 isoform, ∆133p53, protects astrocytes from radiation-induced senescence, promotes DNA repair, and inhibits astrocyte-mediated neuroinflammation.

References

YearCitations

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