Methamphetamine reduces expressions of tight junction proteins, rearranges F-actin cytoskeleton and increases the blood brain barrier permeability via the RhoA/ROCK-dependent pathway

The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton

Alan S. Fanning, Brian J. Jameson, Lynne Jesaitis et al. · Journal of Biological Chemistry · 1998 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Protein Interactions at the Tight Junction

Erika S. Wittchen, Julie Haskins, Bruce R. Stevenson · Journal of Biological Chemistry · 1999 · 478 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood–Brain Barrier Damage in Early Ischemic Stroke Stage

Jie Liu, Xinchun Jin, Ke J. Liu et al. · Journal of Neuroscience · 2012 · 423 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

Gerty Schreibelt, Gijs Kooij, Arie Reijerkerk et al. · The FASEB Journal · 2007 · 353 citations

Life Sciences, Neurobiology, Neuroscience +17

IFN-γ-Induced TNFR2 Expression Is Required for TNF-Dependent Intestinal Epithelial Barrier Dysfunction

Fengjun Wang, Brad T. Schwarz, W. Vallen Graham et al. · Gastroenterology · 2006 · 305 citations · Full text

Life Sciences, Cell Biology, Immunology +14