W. Vallen Graham

Interferon-γ and Tumor Necrosis Factor-α Synergize to Induce Intestinal Epithelial Barrier Dysfunction by Up-Regulating Myosin Light Chain Kinase Expression

Fengjun Wang, W. Vallen Graham, Yingmin Wang et al. · American Journal Of Pathology · 2005 · 672 citations · Full text

Inflammation, Cytokine, Signal Transduction +10

Caveolin-1–dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

Amanda M. Marchiando, Le Shen, W. Vallen Graham et al. · The Journal of Cell Biology · 2010 · 459 citations · Full text

Immunology, Cytoskeleton, Cellular Physiology +17

IFN-γ-Induced TNFR2 Expression Is Required for TNF-Dependent Intestinal Epithelial Barrier Dysfunction

Fengjun Wang, Brad T. Schwarz, W. Vallen Graham et al. · Gastroenterology · 2006 · 297 citations · Full text

Inflammation, Mucosal Immunology, Ifn-γ-induced Tnfr2 Expression +8

The Epithelial Barrier Is Maintained by In Vivo Tight Junction Expansion During Pathologic Intestinal Epithelial Shedding

Amanda M. Marchiando, Le Shen, W. Vallen Graham et al. · Gastroenterology · 2011 · 274 citations · Full text

Epithelial Barrier Is, Gastroenterology, Pathology +11

Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis

W. Vallen Graham, Amanda M. Marchiando, Juanmin Zha et al. · Nature Medicine · 2019 · 159 citations · Full text

Inflammation, Signal Transduction, Mucosal Immunology +10