Concepedia

Blood-brain Barrier Dysfunction

Blood-Brain Barrier Dysfunction is a pathophysiological condition of the cerebral microvasculature in which structural and/or functional alterations of the blood–brain barrier compromise its selective permeability, transport, and signaling properties, thereby disrupting central nervous system homeostasis.

7.9K

Publications

535.1K

Citations

36.1K

Authors

4.8K

Institutions

Publications per year

2017–2026

2.8K

Variants

Blood-brain Barrier Breakdown

Parents

Children

Publications

7.9K

The gut microbiota influences blood-brain barrier permeability in mice

Viorica Braniste, Maha Al‐Asmakh, Czeslawa Kowal et al. · Science Translational Medicine · 2014 · 2.4K citations · Full text

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen et al. · Cell · 1994 · 2.3K citations

, , +14

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

Axel Montagne, Samuel Barnes, Melanie D. Sweeney et al. · Neuron · 2015 · 2.1K citations · Full text

, , +14

Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice

Takehiro Nitta, Masaki Hata, Shimpei Gotoh et al. · The Journal of Cell Biology · 2003 · 1.9K citations

, , +17

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

Hania Kébir, Katharina Kreymborg, Igal Ifergan et al. · Nature Medicine · 2007 · 1.7K citations · Full text

, , +16

1–5 of 7.9K

Authors

36.1K

  1. JH
    John H. Zhang

    Loma Linda University, United States

    75 publications · 5.5K citations

    44

    h-index

  2. WA
    William A. Banks

    Geriatric Research Education and Clinical Center, United States

    54 publications · 5.6K citations

    40

    h-index

  3. AF
    Alon Friedman

    Ben-Gurion University of the Negev, Israel

    48 publications · 6.5K citations

    38

    h-index

  4. BV
    Berislav V. Zloković

    University of Southern California, United States

    40 publications · 12.2K citations

    33

    h-index

  5. HE
    Helga E. de Vries

    Amsterdam UMC Location Vrije Universiteit Amsterdam, Netherlands

    40 publications · 5.7K citations

    33

    h-index

1–5 of 36.1K

Institutions

4.8K

  1. Harvard University

    Cambridge, United States

    66 h-index

    574 publications

    65.3K citations

  2. Inserm

    Paris, France

    57 h-index

    681 publications

    43.4K citations

  3. University of California, San Francisco

    San Francisco, United States

    51 h-index

    304 publications

    31.3K citations

  4. University College London

    London, United Kingdom

    48 h-index

    302 publications

    39.5K citations

  5. National Institutes of Health

    Bethesda, United States

    48 h-index

    329 publications

    29.8K citations

  6. Loma Linda University

    Loma Linda, United States

    48 h-index

    491 publications

    31.8K citations

  7. Neurological Surgery

    Rockville Centre, United States

    47 h-index

    302 publications

    27.5K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    46 h-index

    370 publications

    26.3K citations

1–8 of 4.8K

Venues

  1. Journal of Cerebral Blood Flow & Metabolism

    234 publications · 24K citations

    86

    h-index

  2. Stroke

    193 publications · 20.8K citations

    84

    h-index

  3. Brain Research

    275 publications · 16.5K citations

    73

    h-index

  4. Acta Neuropathologica

    120 publications · 10.5K citations

    58

    h-index

  5. PLoS ONE

    161 publications · 10.2K citations

    57

    h-index

1–5