Jasper Smit

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen et al. · Cell · 1994 · 2.3K citations

Molecular Pharmacology, Medicine, P-glycoprotein Gene +6

Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

Jasper Smit, Alfred H. Schinkel, Ronald P.J. Oude Elferink et al. · Cell · 1993 · 1.5K citations

Hepatology, Biochemistry, Biliary Tract +11

Analysis of the expression of MRP, the gene for a new putative transmembrane drug transporter, in human multidrug resistant lung cancer cell lines

G J Zaman, C. H. M. Versantvoort, Jasper Smit et al. · Lung Cancer · 1994 · 314 citations

Medicine, Cancer Biology, Anti-cancer Agent +6

The human MDR3 P‐glycoprotein promotes translocation of phosphatidylcholine through the plasma membrane of fibroblasts from transgenic mice

Alexander J. Smith, Johanna L.P.M. Timmermans-Hereijgers, B. Roelofsen et al. · FEBS Letters · 1994 · 276 citations · Full text

Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.

Ronald P.J. Oude Elferink, R. Ottenhoff, M van Wijland et al. · Journal of Clinical Investigation · 1995 · 223 citations · Full text

Lipid Movement, Cholangiopathies, Cholesterol Secretion +23