Concepedia

Rapamycin-inspired macrocycles with new target specificity

Zufeng Guo, Sam Y. Hong, Jingxin Wang, Shahid Rehan, Wukun Liu, Hanjing Peng, Manisha Das, Wei Li, Shridhar Bhat, Brandon Peiffer,

Nature Chemistry · 2018 · 124 citations · 41 references

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41

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

, , +8

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

Joseph Heitman, N. Rao Movva, Michael N. Hall · Science · 1991 · 2K citations

, , +17

A new type of synthetic peptide library for identifying ligand-binding activity

Kit S. Lam, Sydney E. Salmon, Evan M. Hersh et al. · Nature · 1991 · 1.8K citations

, , +16

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

Günter Fischer, Brigitte Wittmann‐Liebold, Kurt Lang et al. · Nature · 1989 · 1.4K citations

, , +5

A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

Matthew W. Harding, David Uehling, Stuart L. Schreiber · Nature · 1989 · 1.4K citations

, , +8