Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin

Tilman Schneider‐Poetsch, Jianhua Ju, Daniel E. Eyler, +6

Nature Chemical Biology

BiosynthesisProtein BiosynthesisMolecular BiologyEukaryotic Translation ElongationProtein Synthesis +1

XPB, a subunit of TFIIH, is a target of the natural product triptolide

Denis V. Titov, Benjamin Gilman, Qingli He, +9

Nature Chemical Biology

Protein FunctionNatural SciencesProtein BiosynthesisMolecular BiologyMolecular Genetics +3

The HBV Drug Entecavir — Effects on HIV-1 Replication and Resistance

Moira A. McMahon, Benjamin L. Jilek, Timothy Brennan, +11

New England Journal of Medicine

Hiv-1 RnaHuman RetrovirusViral Polymerase MechanismImmunologyAntiviral Response +11

Inhibition of Angiogenesis by the Antifungal Drug Itraconazole

Curtis R. Chong, Jing Xu, Jun Lu, +3

ACS Chemical Biology

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4 ⁺ T Cell Model without Inducing Global T Cell Activation

Sifei Xing, C. Korin Bullen, Neeta S. Shroff, +10

Journal of Virology

Adaptive Immune SystemImmune RegulationImmunologyImmunodominanceCd4 T Cell Responses +16

Rapamycin-inspired macrocycles with new target specificity

Zufeng Guo, Sam Y. Hong, Jingxin Wang, +16

Nature Chemistry

Combinatorial ChemistryNatural SciencesRational Drug DesignMolecular BiologyNew Target Specificity +2

Effect of Nitroxoline on Angiogenesis and Growth of Human Bladder Cancer

Joong Sup Shim, Yoshiyuki Matsui, Shridhar Bhat, +9

JNCI Journal of the National Cancer Institute

Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase

Martin Krátký, Jarmila Vinšová, Eva Novotná, +7

Tuberculosis

Pulmonary TuberculosisBlock Mycobacterium TuberculosisBiochemistryHealth SciencesMethionine Aminopeptidase +10

Optimization of the Potency and Pharmacokinetic Properties of a Macrocyclic Ghrelin Receptor Agonist (Part I): Development of Ulimorelin (TZP-101) from Hit to Clinic

Hamid R. Hoveyda, Éric Marsault, René Gagnon, +19

Journal of Medicinal Chemistry

Pharmaceutical ScienceQuantitative PharmacologyPharmacotherapyExperimental PharmacologyPre-clinical Pharmacology +19

Reaction of Azides with Tetrathiomolybdate: Reduction and Imine Formation

A. R. Ramesha, Shridhar Bhat, Srinivasan Chandrasekaran

The Journal of Organic Chemistry

AltmetricsInorganic ChemistryImine FormationaEngineeringHeterocyclic +12