An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients

Celsa A. Spina, Jenny L. Anderson, Nancie M. Archin, +20

PLoS Pathogens

The HBV Drug Entecavir — Effects on HIV-1 Replication and Resistance

Moira A. McMahon, Benjamin L. Jilek, Timothy Brennan, +11

New England Journal of Medicine

Hiv-1 RnaHuman RetrovirusViral Polymerase MechanismImmunologyAntiviral Response +11

Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation

Hung‐Chih Yang, Sifei Xing, Liang Shan, +10

Journal of Clinical Investigation

EngineeringReverse LatencyImmunologyMolecular BiologyImmunotherapy +18

BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism

Daniela Boehm, Vincenzo Calvanese, Roy D. Dar, +12

Cell Cycle

ImmunologyMolecular BiologyHiv TranscriptionAntiviral DrugImmunotherapy +17

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4 ⁺ T Cell Model without Inducing Global T Cell Activation

Sifei Xing, C. Korin Bullen, Neeta S. Shroff, +10

Journal of Virology

Adaptive Immune SystemImmune RegulationImmunologyImmunodominanceCd4 T Cell Responses +16

Transcriptional Reprogramming during Effector-to-Memory Transition Renders CD4+ T Cells Permissive for Latent HIV-1 Infection

Liang Shan, Kai Deng, Hongbo Gao, +16

Immunity

Latent Hiv-1 InfectionHuman RetrovirusImmunologyAntiviral ResponseHiv +4

A Critical Subset Model Provides a Conceptual Basis for the High Antiviral Activity of Major HIV Drugs

Lin Shen, S. Alireza Rabi, Ahmad R. Sedaghat, +4

Science Translational Medicine

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

Sifei Xing, Shridhar Bhat, Neeta S. Shroff, +5

Journal of Antimicrobial Chemotherapy

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells

Liang Shan, Sifei Xing, Hung‐Chih Yang, +3

Journal of Antimicrobial Chemotherapy