In vitro and in vivo studies of oxidative stress responses against acrylamide toxicity in zebrafish

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

Masaaki Komatsu, Satoshi Waguri, Keiko Taguchi et al. · Nature Cell Biology · 2010 · 2.4K citations

Life Sciences, Cell Biology, Molecular Biology +14

Analysis of Acrylamide, a Carcinogen Formed in Heated Foodstuffs

Eden Tareke, Per Rydberg, Patrik Karlsson et al. · Journal of Agricultural and Food Chemistry · 2002 · 2.2K citations

Agriculture, Food Science, Toxicology +17

Nrf2, a Cap'n'Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene

Jawed Alam, Daniel P. Stewart, Cheri Touchard et al. · Journal of Biological Chemistry · 1999 · 1.3K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase ₁  gene

Venugopal Radjendirane, Anil K. Jaiswal · Proceedings of the National Academy of Sciences · 1996 · 1K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Molecular Cloning, Characterization, and Expression in Escherichia coli of Full-length cDNAs of Three Human Glutathione S-Transferase Pi Gene Variants

Francis Ali‐Osman, Olanike Akande, Gamil R. Antoun et al. · Journal of Biological Chemistry · 1997 · 722 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11