Concepedia

PINK1-dependent mitophagy is driven by the UPS and can occur independently of LC3 conversion

Aleksandar Raković, Jonathan D. Ziegler, Christoph U. Mårtensson, Jannik Prasuhn, Katharina Shurkewitsch, Peter König, Henry L. Paulson, Christine Klein

Cell Death and Differentiation · 2018 · 69 citations · 33 references

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33

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

Derek P. Narendra, Atsushi Tanaka, Der‐Fen Suen et al. · The Journal of Cell Biology · 2008 · 4K citations · Full text

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PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

, , +17

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Sven Geisler, Kira M. Holmström, Diana Skujat et al. · Nature Cell Biology · 2010 · 2.8K citations

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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Michael Lazarou, Danielle A. Sliter, Lesley A. Kane et al. · Nature · 2015 · 2.7K citations

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

Sheila A. Stewart, Derek M. Dykxhoorn, Deborah Palliser et al. · RNA · 2003 · 1.6K citations · Full text

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