Concepedia

Lecithin–chitosan–TPGS nanoparticles as nanocarriers of (−)-epicatechin enhanced its anticancer activity in breast cancer cells

Adriana Guadalupe Pérez Ruiz, Adriana Ganem‐Rondero, Ivonne María Olivares-Corichi, José Rubén García-Sánchez

RSC Advances · 2018 · 67 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

that was four-fold lower (85 μM) than free (-)-epicatechin (350 μM) and showed selectivity to cancerous cells. This study demonstrated that encapsulating (-)-epicatechin into lecithin-chitosan nanoparticles opens new options for breast cancer treatment.

References

29

Chitosan—A versatile semi-synthetic polymer in biomedical applications

Mamoni Dash, Raphael M. Ottenbrite, Emo Chiellini · Progress in Polymer Science · 2011 · 2.8K citations

, , +14

Interactions between Alginate and Chitosan Biopolymers Characterized Using FTIR and XPS

Gwendolyn Lawrie, Imelda Keen, Barry R. Drew et al. · Biomacromolecules · 2007 · 1.4K citations

, , +16

(–)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans

Hagen Schroeter, Jan C. Balzer, Petra Kleinbongard et al. · Proceedings of the National Academy of Sciences · 2006 · 1K citations

, , +16

Catechin, epicatechin, quercetin, rutin and resveratrol in red grape: Content, in vitro antioxidant activity and interactions

Patrizia Iacopini, Massimiliano Baldi, Paolo Storchi et al. · Journal of Food Composition and Analysis · 2008 · 505 citations

, , +11

Flavor Chemistry of Cocoa and Cocoa Products—An Overview

Ana Clara Aprotosoaie, Simon Vlad Luca, Anca Miron · Comprehensive Reviews in Food Science and Food Safety · 2015 · 479 citations

, , +13