Concepedia

Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep

Marcela Vilariño, Fabian P. Suchy, S. Tamir Rashid, Helen Lindsay, Juan Reyes, Bret R. McNabb, Talitha van der Meulen, Mark O. Huising, Hiromitsu Nakauchi, Pablo J. Ross

Transgenic Research · 2018 · 40 citations · 24 references

DOI

Concepts

References

24

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

, , +17

Minimap2: pairwise alignment for nucleotide sequences

Heng Li · Bioinformatics · 2018 · 16.8K citations · Full text

, , +17

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

Haoyi Wang, Hui Yang, Chikdu Shivalila et al. · Cell · 2013 · 3.6K citations · Full text

, , +14

Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells

Toshihiro Kobayashi, Tomoyuki Yamaguchi, Sanae Hamanaka et al. · Cell · 2010 · 579 citations · Full text

, , +16

Interspecies Chimerism with Mammalian Pluripotent Stem Cells

Jun Wu, Aida Platero-Luengo, Masahiro Sakurai et al. · Cell · 2017 · 500 citations · Full text

, , +8