Concepedia

Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival

Gaurav Pathria, David A. Scott, Yongmei Feng, Joo Sang Lee, Yu Fujita, Gao Zhang, Avinash Sahu, Eytan Ruppin, Meenhard Herlyn, Andrei L. Osterman,

The EMBO Journal · 2018 · 159 citations · 35 references

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35

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Itay Tirosh, Benjamin Izar, Sanjay M. Prakadan et al. · Science · 2016 · 5.2K citations · Full text

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An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

Heather P. Harding, Yuhong Zhang, Huiquing Zeng et al. · Molecular Cell · 2003 · 3.3K citations · Full text

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A Landscape of Driver Mutations in Melanoma

Eran Hodis, Ian R. Watson, Gregory V. Kryukov et al. · Cell · 2012 · 2.6K citations · Full text

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Ping Gao, Irina Tchernyshyov, Tsung-Cheng Chang et al. · Nature · 2009 · 2.1K citations · Full text

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

David R. Wise, Ralph J. DeBerardinis, Anthony Mancuso et al. · Proceedings of the National Academy of Sciences · 2008 · 2K citations · Full text

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