Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Itay Tirosh, Benjamin Izar, Sanjay M. Prakadan, +33

Science

Melanoma TumorsImmunologyBiological MicroenvironmentsTumor BiologyOncology +17

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

Christopher J. Nirschl, Mayte Suárez‐Fariñas, Benjamin Izar, +26

Cell

Ifnγ-dependent Tissue-immune HomeostasisCancer ImmunosurveillanceImmunologyImmune RegulationTumor Immunity +4

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

Alex S. Genshaft, Shuqiang Li, Caroline J. Gallant, +10

Genome biology

PI3Kβ controls immune evasion in PTEN-deficient breast tumours

Johann S. Bergholz, Qiwei Wang, Qi Wang, +19

Nature

Immune EvasionSignaling PathwayImmune RegulationTumor ImmunityImmunology +6

Linking single-cell measurements of mass, growth rate, and gene expression

Robert Kimmerling, Sanjay M. Prakadan, Alejandro Gupta, +10

Genome biology

Growth Rate UpstreamCell GrowthGliomaCellular PhysiologyTrajectory Analysis +16

Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer

Bashar Hamza, Sheng Rong Ng, Sanjay M. Prakadan, +21

Proceedings of the National Academy of Sciences

EngineeringCtc IsolationTumor CellsOrgan-on-a-chipBiomedical Engineering +20

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Sanjay M. Prakadan, Christopher Alvarez‐Breckenridge, Samuel C. Markson, +26

Nature Communications

Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents

Chen Lossos, Yunpeng Liu, Kellie E. Kolb, +21

Cancer Discovery

MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection

Sharon Khuzwayo, Maphe Mthembu, Erin W. Meermeier, +15

Frontiers in Immunology

Phase II study of pembrolizumab in leptomeningeal carcinomatosis.

Priscilla K. Brastianos, Sanjay M. Prakadan, Christopher Alvarez‐Breckenridge, +17

Journal of Clinical Oncology

Neuro-oncologyMalignant DiseaseMedicineCancer ManagementSerial Csf +12