Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Yukihiro Furusawa, Yuuki Obata, Shinji Fukuda, +27

Nature

InflammationMucosal ImmunologyCommensal Microbe-derived ButyrateT-regulatory CellImmunology +8

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T _reg Cell Homeostasis

Patrick M. Smith, Michael R. Howitt, Nicolai Panikov, +5

Science

DysbiosisHost-microbe InteractionsImmunologyRegulatory T CellsInflammation +18

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

Nicholas Arpaia, Clarissa Campbell, Xiying Fan, +8

Nature

Microbial PathogensT-regulatory CellPathogenesisImmunologyBacteriology +7

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

Aurélien Trompette, Eva S. Gollwitzer, Koshika Yadava, +8

Nature Medicine

AsthmaNutritionMicrobiota FunctionDysbiosisAllergy +12

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

Nagendra Singh, Ashish Gurav, Sathish Sivaprakasam, +10

Immunity

InflammationSuppresses Colonic InflammationMedicineCommensal Metabolite ButyrateImmunology +8

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

Chih‐Hao Chang, Jonathan D. Curtis, Leonard B. Maggi, +11

Cell

Signal TransductionAerobic GlycolysisCell SignalingBioenergeticsPhysiology +6

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin

Andrew M. Intlekofer, Naofumi Takemoto, E. John Wherry, +15

Nature Immunology

Signal TransductionLymphocyte DevelopmentT-regulatory CellImmunologyAutoimmunity +5

Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR–S6K pathway

Jason Y. Park, Myunghoo Kim, Seung Goo Kang, +4

Mucosal Immunology

Short-Chain Fatty Acids Activate GPR41 and GPR43 on Intestinal Epithelial Cells to Promote Inflammatory Responses in Mice

Myung H. Kim, Seung Goo Kang, Jeong H. Park, +2

Gastroenterology

InflammationInflammatory ResponsesMolecular PhysiologyMucosal ImmunologyImmunology +6

Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

Aiden Haghikia, Stefanie Jörg, Alexander Duscha, +19

Immunity

InflammationNutritionAutoimmune DiseaseSmall IntestineMedicine +6