Regulation of the effector function of CD8+ T cells by gut microbiota-derived metabolite butyrate

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Yukihiro Furusawa, Yuuki Obata, Shinji Fukuda et al. · Nature · 2013 · 5.1K citations

Inflammation, Mucosal Immunology, Commensal Microbe-derived Butyrate +10

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T _reg Cell Homeostasis

Patrick M. Smith, Michael R. Howitt, Nicolai Panikov et al. · Science · 2013 · 5.1K citations · Full text

Dysbiosis, Host-microbe Interactions, Immunology +20

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

Nicholas Arpaia, Clarissa Campbell, Xiying Fan et al. · Nature · 2013 · 4.5K citations · Full text

Microbial Pathogens, T-regulatory Cell, Pathogenesis +9

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

Aurélien Trompette, Eva S. Gollwitzer, Koshika Yadava et al. · Nature Medicine · 2014 · 2.7K citations · Full text

Asthma, Nutrition, Microbiota Function +14

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

Nagendra Singh, Ashish Gurav, Sathish Sivaprakasam et al. · Immunity · 2014 · 2.2K citations · Full text

Inflammation, Suppresses Colonic Inflammation, Medicine +10