The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T _reg Cell Homeostasis

Patrick M. Smith, Michael R. Howitt, Nicolai Panikov, +5

Science

DysbiosisHost-microbe InteractionsImmunologyRegulatory T CellsInflammation +18

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel, +14

Cell

DysbiosisMucosal ImmunologyMicrobiologyGut BarrierMicrobiome +3

Induction of Colonic Regulatory T Cells by Indigenous <i>Clostridium</i> Species

Koji Atarashi, Takeshi Tanoue, Tatsuichiro Shima, +14

Science

DysbiosisMicrobial PathogensT-regulatory CellImmune RegulationImmunology +21

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Kendle M. Maslowski, Angélica T. Vieira, Aylwin Ng, +10

Nature

InflammationInflammatory ResponsesDysbiosisMucosal ImmunologyHost-microbe Interactions +10

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

Koji Atarashi, Takeshi Tanoue, Kenshiro Oshima, +19

Nature

BiologyMedical MicrobiologyMicrobial DiseaseTreg InductionClostridia Strains +7

Regulatory T Cell Lineage Specification by the Forkhead Transcription Factor Foxp3

Jason D. Fontenot, Jeffrey P. Rasmussen, Luke M. Williams, +3

Immunity

Transcriptional RegulationLineage PlasticityDevelopmental BiologyGeneticsT-regulatory Cell +7

Inducible Foxp3 ⁺ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

June L. Round, Sarkis K. Mazmanian

Proceedings of the National Academy of Sciences

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Jeong Kim, Jeffrey P. Rasmussen, Alexander Y. Rudensky

Nature Immunology

InflammationAutoimmune DiseaseT-regulatory CellImmunologyRegulatory T Cells +9

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Ye Zheng, Steven Z. Josefowicz, Ashutosh Chaudhry, +3

Nature

ChromatinTranscriptional RegulationGeneticsT-regulatory CellTranscription Regulation +11

Peripheral education of the immune system by colonic commensal microbiota

Stephanie K. Lathrop, Seth M. Bloom, Sindhuja Rao, +6

Nature

DysbiosisMucosal ImmunologyMicrobiotaImmunologyGut Microbiology +8