Concepedia

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

Daniela Latorre, Ulf Kallweit, Eric Armentani, Mathilde Foglierini, Federico Mele, Antonino Cassotta, Sandra Jovic, David Jarrossay, Johannes Mathis, Francesco Zellini,

Nature · 2018 · 334 citations · 33 references

DOI

Concepts

References

33

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Christelle Peyron, Juliette Faraco, William M. Rogers et al. · Nature Medicine · 2000 · 2.1K citations

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Reduced Number of Hypocretin Neurons in Human Narcolepsy

Thomas C. Thannickal, Robert Y. Moore, Robert Nienhuis et al. · Neuron · 2000 · 2.1K citations · Full text

, , +12

Narcolepsy is strongly associated with the T-cell receptor alpha locus

Joachim Hallmayer, Juliette Faraco, Ling Lin et al. · Nature Genetics · 2009 · 481 citations · Full text

, , +11

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

Sally C. Kent, Yahua Chen, Lisa Bregoli et al. · Nature · 2005 · 413 citations

, , +14

HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients.

Emmanuel Mignot, R. Hayduk, Jed Black et al. · PubMed · 1997 · 364 citations

, , +13