Impairment of immunity to <i>Candida</i> and <i>Mycobacterium</i> in humans with bi-allelic <i>RORC</i> mutations

Satoshi Okada, Janet Markle, Elissa K. Deenick, +48

Science

Functional heterogeneity of human memory CD4 ⁺ T cell clones primed by pathogens or vaccines

Simone Becattini, Daniela Latorre, Federico Mele, +9

Science

Polarized ResponsesAdaptive Immune SystemT-regulatory CellImmunologyImmune Regulation +18

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

Daniela Latorre, Ulf Kallweit, Eric Armentani, +14

Nature

MedicineT-regulatory CellImmunologyNarcolepsy Target Self-antigensNeuropeptide Receptor +13

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

Rubén Martínez‐Barricarte, Janet Markle, S. Cindy, +49

Science Immunology

Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria

Rui Yang, Federico Mele, Lisa Worley, +48

Cell

Host ResponseMicrobial PathogensAdaptive Immune SystemPathogenesisImmunology +11

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency

Xiao‐Fei Kong, Rubén Martínez‐Barricarte, James Kennedy, +38

Nature Immunology

PathogenesisImmunologyAntimycobacterial CircuitAutoimmunityHelper T Cells +7

Human CD4+ T cell subsets differ in their abilities to cross endothelial and epithelial brain barriers in vitro

Hideaki Nishihara, Sasha Soldati, Adrien Mossu, +12

Fluids and Barriers of the CNS

Bovine Lactoferrin Counteracts Toll-Like Receptor Mediated Activation Signals in Antigen Presenting Cells

Patrizia Puddu, Daniela Latorre, Maria Carollo, +4

PLoS ONE

Immune ActivationAdaptive Immune SystemInnate Immune SystemImmunologyImmune Regulation +22

Autoreactive T cells target peripheral nerves in Guillain–Barré syndrome

Lenka Súkeníková, Anna Mallone, Bettina Schreiner, +6

Nature

ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells

Federico Mele, Camilla Basso, Cristina Leoni, +6

Nature Communications