Janet Markle

Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

Janet Markle, Daniel N. Frank, Steven Mortin-Toth et al. · Science · 2013 · 2K citations · Full text

Life Sciences, Endocrinology, Immunology +17

Impairment of immunity to <i>Candida</i> and <i>Mycobacterium</i> in humans with bi-allelic <i>RORC</i> mutations

Satoshi Okada, Janet Markle, Elissa K. Deenick et al. · Science · 2015 · 415 citations · Full text

Life Sciences, Immunology, Microbiology +17

The human gene damage index as a gene-level approach to prioritizing exome variants

Yuval Itan, Lei Shang, Bertrand Boisson et al. · Proceedings of the National Academy of Sciences · 2015 · 279 citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common <i>TYK2</i> missense variant

Stéphanie Boisson‐Dupuis, Noé Ramirez‐Alejo, Zhi Li et al. · Science Immunology · 2018 · 209 citations · Full text

Life Sciences, Genetics, Immunology +13

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

Rubén Martínez‐Barricarte, Janet Markle, S. Cindy et al. · Science Immunology · 2018 · 197 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17