Lei Shang

Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants

Aziz Belkadi, Alexandre Bolze, Yuval Itan et al. · Proceedings of the National Academy of Sciences · 2015 · 644 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

The human gene damage index as a gene-level approach to prioritizing exome variants

Yuval Itan, Lei Shang, Bertrand Boisson et al. · Proceedings of the National Academy of Sciences · 2015 · 279 citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Genetic Diagnosis Using Whole Exome Sequencing in Common Variable Immunodeficiency

Patrick Maffucci, Charles A. Filion, Bertrand Boisson et al. · Frontiers in Immunology · 2016 · 267 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis

Patrick Maffucci, Benedetta Bigio, Franck Rapaport et al. · Proceedings of the National Academy of Sciences · 2018 · 72 citations · Full text

Life Sciences, Bioinformatics, Genetics +16

Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage

Aziz Belkadi, Vincent Pedergnana, Aurélie Cobat et al. · Proceedings of the National Academy of Sciences · 2016 · 71 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17