The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies - Concepedia

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The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies

49

Citations

31

References

2018

Year

Matthew C. Stubbs, Timothy C. Burn, Richard Sparks, Thomas Maduskuie, Sharon Diamond, Mark Rupar, Xiaoming Wen, Alla Volgina, Nina Zolotarjova, Paul Waeltz,

Clinical Cancer Research

Abstract

Preclinical data reveal insights into vulnerabilities created in myeloma cells by BET protein inhibition and potential strategies that can be leveraged in clinical studies to enhance the activity of INCB054329.

References

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