Assessment of the cytotoxic potential of an aqueous-ethanolic extract from <i>Thalassia testudinum</i> angiosperm marine grown in the Caribbean Sea

Abstract

Thalassia testudinum extract is more cytotoxic and produced more DNA damage on human hepatoma cells than to other non-tumour cells. A possible mechanism is suggested for extract-induced cytotoxicity based on oxidative stress, nuclear damage and hypercalcaemia in HepG2 cells. T. testudinum may be a source for antitumour agents.