Aditi U. Gurkar

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

Yi Zhu, Tamar Tchkonia, Tamar Pirtskhalava et al. · Aging Cell · 2015 · 2.4K citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Lakshmi Raj, Takao Ide, Aditi U. Gurkar et al. · Nature · 2011 · 1K citations

Medicine, Cancer Biology, Oncology +15

Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice

Matthew J. Yousefzadeh, Jing Zhao, Christina Bukata et al. · Aging Cell · 2020 · 324 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging

Andria R. Robinson, Matthew J. Yousefzadeh, Tania A. Rozgaja et al. · Redox Biology · 2018 · 166 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress

Aditi U. Gurkar, Kiki Chu, Lakshmi Raj et al. · Nature Communications · 2013 · 158 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14