Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Lakshmi Raj, Takao Ide, Aditi U. Gurkar, +11

Nature

Tumor BiologyDrug TargetingSelective KillingMedicineSmall Molecules +10

Tumor–stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c‐Met pathway

Takao Ide, Yoshihiko Kitajima, Atsushi Miyoshi, +5

International Journal of Cancer

Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c‐Met system via hypoxia inducible factor‐1 in pancreatic cancer

Yoshihiko Kitajima, Takao Ide, Takao Ohtsuka, +1

Cancer Science

The Hypoxic Environment in Tumor-Stromal Cells Accelerates Pancreatic Cancer Progression via the Activation of Paracrine Hepatocyte Growth Factor/c-Met Signaling

Takao Ide, Yoshihiko Kitajima, Atsushi Miyoshi, +4

Annals of Surgical Oncology

Cancer ResearchPancreatic CancerMedicineLiver PhysiologyLiver Cancer +8

RETRACTED: GAMT, a p53-Inducible Modulator of Apoptosis, Is Critical for the Adaptive Response to Nutrient Stress

Takao Ide, Lauren Brown‐Endres, Kiki Chu, +5

Molecular Cell

Reductive StressMitophagyNutrient StressPhysiologyAutophagy +9

Transferrin receptor 1 overexpression is associated with tumour de‐differentiation and acts as a potential prognostic indicator of hepatocellular carcinoma

Makiko Adachi, Keita Kai, Koutaro Yamaji, +4

Histopathology

Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1α-independent manner

Anderson Miyoshi, Yoshihiko Kitajima, Takao Ide, +5

International Journal of Oncology

Mmp FamilyPathologyCancer BiologyTumor BiologyCancer Cell Biology +14

Clinicopathologic features of advanced gallbladder cancer associated with adenomyomatosis

Keita Kai, Takao Ide, Masanori Masuda, +5

Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin

Surgical OncologyGastrointestinal OncologyBiliary TractMedicineBiliary Cancer +8

Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients

Mayumi Mitsuno, Yoshihiko Kitajima, Takao Ide, +4

Journal of Gastroenterology

Aberrant MethylationOncologyGastrointestinal OncologyMedicineGastric Cancer Patients +8

Clinicopathological characteristics of combined hepatocellular cholangiocarcinoma from the viewpoint of patient prognosis after hepatic resection: High rate of early recurrence and its predictors

Yo‐ichi Yamashita, Shinichi Aishima, Yosuke Nakao, +14

Hepatology Research