Lakshmi Raj

Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Lakshmi Raj, Takao Ide, Aditi U. Gurkar et al. · Nature · 2011 · 1K citations

Tumor Biology, Drug Targeting, Selective Killing +12

Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing

Marie-Cécile Didiot, Lauren M Hall, Andrew H. Coles et al. · Molecular Therapy · 2016 · 464 citations · Full text

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

Julien Fitamant, Filippos Kottakis, Samira Benhamouche et al. · Cell Reports · 2015 · 247 citations · Full text

Tumor Regression, Pathology, Hcc Pathogenesis +21

Hzf Determines Cell Survival upon Genotoxic Stress by Modulating p53 Transactivation

Sanjeev Das, Lakshmi Raj, Bo Zhao et al. · Cell · 2007 · 160 citations · Full text

Reductive Stress, Genome Instability, Genotoxic Stress +10

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress

Aditi U. Gurkar, Kiki Chu, Lakshmi Raj et al. · Nature Communications · 2013 · 157 citations · Full text

Reductive Stress, Cell Autophagy, Mitophagy +15