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Sodium chloride is an ionic checkpoint for human T <sub>H</sub> 2 cells and shapes the atopic skin microenvironment

Julia Matthias, Rebecca Noster, Hanna Meinl, Ying-Yin Chao, H. Gerstenberg, Florian Jeschke, Gilles Gasparoni, Anna Welle, Jörn Walter, Karl Nordström,

Science Translational Medicine · 2019 · 102 citations · 36 references

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Abstract

Sodium chloride induces and amplifies human T H 2 cell responses, potentially shaping the atopic skin microenvironment.

References

36

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love, Wolfgang Huber, Simon Anders · Genome biology · 2014 · 100.5K citations · Full text

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STAR: ultrafast universal RNA-seq aligner

Alexander Dobin, Carrie Davis, Felix Schlesinger et al. · Bioinformatics · 2012 · 56.2K citations · Full text

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Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

Markus Kleinewietfeld, Arndt Manzel, Jens Titze et al. · Nature · 2013 · 1.4K citations · Full text

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Salt-responsive gut commensal modulates TH17 axis and disease

Nicola Wilck, Mariana Matus, Sean M. Kearney et al. · Nature · 2017 · 1.3K citations · Full text

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The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

Greg M. Delgoffe, Kristen Pollizzi, Adam T. Waickman et al. · Nature Immunology · 2011 · 1.1K citations · Full text

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