Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, Amanuel Alemu Abajobir, Kalkidan Hassen Abate et al. · The Lancet · 2017 · 13.5K citations · Full text

Public Health, Health Sciences, Epidemiologic Methods +16

Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart Study

Daniel Levy, Robert J. Garrison, Daniel D. Savage et al. · New England Journal of Medicine · 1990 · 5.7K citations · Full text

Medicine, Cardiology, Internal Medicine +17

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Zeneng Wang, Elizabeth Klipfell, Brian J. Bennett et al. · Nature · 2011 · 5.6K citations

Life Sciences, Cardiology, Physiology +10

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

Robert Koeth, Zeneng Wang, Bruce S. Levison et al. · Nature Medicine · 2013 · 4.4K citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +11

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

Weifei Zhu, Jill C. Gregory, Elin Org et al. · Cell · 2016 · 1.9K citations · Full text

Life Sciences, Immunology, Microbiology +12