Concepedia

Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced Neovascularization

Yosif Manavski, Tina Lucas, Simone-Franziska Glaser, Lena Dorsheimer, Stefan Günther, Thomas Braun, Michael A. Rieger, Andreas M. Zeiher, Reinier A. Boon, Stefanie Dimmeler

Circulation Research · 2018 · 124 citations · 17 references

DOIFull text

Open access

Abstract

Our data suggest that neovascularization after ischemia is partially mediated by clonal expansion of ECs. Identification of the pathways that control clonal expansion may provide novel tools to augment therapeutic neovascularization or treat pathological angiogenesis.

References

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