The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao, +12

Cell

Regenerative MedicineEpithelial-mesenchymal TransitionDevelopmental BiologyMedicineAdult Stem Cell +7

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

Danwei Huangfu, René Maehr, Wenjun Guo, +4

Nature Biotechnology

Tissue EngineeringDefined FactorsInduced Pluripotent Stem CellPluripotent Stem CellsEngineering +10

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

Danwei Huangfu, Kenji Osafune, René Maehr, +5

Nature Biotechnology

Regenerative MedicineInduced Pluripotent Stem CellDevelopmental BiologyPluripotent Stem CellsMedicine +7

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

Wenjun Guo, Zuzana Keckesova, Joana Liu Donaher, +11

Cell

Embryonic Stem CellCell LineageDevelopmental BiologyCell DivisionMedicine +8

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

Christina Scheel, Elinor Ng Eaton, Hsin‐Jung Li, +8

Cell

Breast OncologyDevelopmental BiologySignal TransductionMaintain MesenchymalMedicine +11

β4 Integrin Amplifies ErbB2 Signaling to Promote Mammary Tumorigenesis

Wenjun Guo, Yuliya Pylayeva, Angela Pepe, +4

Cell

Breast OncologySignal TransductionSignaling PathwayCell-matrix InteractionBreast Cancer +5

Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells

Wai Leong Tam, Haihui Lu, Joyce Y. Buikhuisen, +12

Cancer Cell

Breast OncologySignal TransductionSignaling PathwayCell RegulationMedicine +9

Integrin-Specific Activation of Rac Controls Progression through the G1 Phase of the Cell Cycle

Amel Mettouchi, Sharon Klein, Wenjun Guo, +4

Molecular Cell

Signal TransductionCell RegulationCell DivisionRac Controls ProgressionCell-matrix Interaction +7

Integrin β4 signaling promotes tumor angiogenesis

Sotiris N. Nikolopoulos, Pamela Blaikie, Toshiaki Yoshioka, +2

Cancer Cell

AngiogenesisMedicineCell-matrix InteractionVascular BiologyMatrix Biology +4

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment

Ping Wang, Mingyan Lin, Erika Pedrosa, +5

Molecular Autism