Concepedia

Elucidating the effects of arginine and lysine on a monoclonal antibody C-terminal lysine variation in CHO cell cultures

Xintao Zhang, Hongping Tang, Yating Sun, Xuping Liu, Wen‐Song Tan, Fan Li

Applied Microbiology and Biotechnology · 2015 · 26 citations · 29 references

DOI

Concepts

References

29

Towards quantitative metabolomics of mammalian cells: Development of a metabolite extraction protocol

Stefanie Dietmair, Nicholas Timmins, Peter P. Gray et al. · Analytical Biochemistry · 2010 · 324 citations

, , +15

Amino acid and glucose metabolism in fed‐batch CHO cell culture affects antibody production and glycosylation

Yuzhou Fan, Ioscani Jiménez del Val, Christian Müller et al. · Biotechnology and Bioengineering · 2014 · 208 citations

, , +16

Intracellular pH of the mouse preimplantation embryo: amino acids act as buffers of intracellular pH

L. J. Edwards, David A. Williams, David K. Gardner · Human Reproduction · 1998 · 162 citations

, , +17

C‐terminal lysine variants in fully human monoclonal antibodies: Investigation of test methods and possible causes

Lawrence W. Dick, Difei Qiu, David Mahon et al. · Biotechnology and Bioengineering · 2008 · 156 citations

, , +11

An investigation of intracellular glycosylation activities in CHO cells: Effects of nucleotide sugar precursor feeding

Niki S.C. Wong, Lydia Wati, Peter Morin Nissom et al. · Biotechnology and Bioengineering · 2010 · 138 citations

, , +17