Ioscani Jiménez del Val

Amino acid and glucose metabolism in fed‐batch CHO cell culture affects antibody production and glycosylation

Yuzhou Fan, Ioscani Jiménez del Val, Christian Müller et al. · Biotechnology and Bioengineering · 2014 · 199 citations

A dynamic mathematical model for monoclonal antibody N‐linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

Ioscani Jiménez del Val, Judit Nagy, Cleo Kontoravdi · Biotechnology Progress · 2011 · 133 citations

Moving towards an era of hybrid modelling: advantages and challenges of coupling mechanistic and data-driven models for upstream pharmaceutical bioprocesses

Apostolos Tsopanoglou, Ioscani Jiménez del Val · Current Opinion in Chemical Engineering · 2021 · 95 citations · Full text

Engineering, Modeling Method, Hybrid Modelling Strategies +27

Towards Controlling the Glycoform: A Model Framework Linking Extracellular Metabolites to Antibody Glycosylation

Philip Jedrzejewski, Ioscani Jiménez del Val, Antony Constantinou et al. · International Journal of Molecular Sciences · 2014 · 82 citations · Full text

Glycobiology, Saturation Kinetics Rates, Metabolic Model +18

Model‐based optimization of antibody galactosylation in CHO cell culture

Pavlos Kotidis, Philip Jedrzejewski, Si Nga Sou et al. · Biotechnology and Bioengineering · 2019 · 82 citations