Concepedia

Metformin reverses established lung fibrosis in a bleomycin model

Sunad Rangarajan, Nathaniel B. Bone, Anna A. Zmijewska, Shaoning Jiang, Dae Won Park, Karen Bernard, Morgan L. Locy, Saranya Ravi, Jessy S. Deshane, Roslyn B. Mannon,

Nature Medicine · 2018 · 577 citations · 29 references

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29

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

New England Journal of Medicine · 2002 · 19K citations · Full text

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova et al. · Science · 2010 · 2.6K citations

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NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

Louise Hecker, Ragini Vittal, Tamara R. Jones et al. · Nature Medicine · 2009 · 844 citations · Full text

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Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance

Louise Hecker, Naomi J. Logsdon, Deepali Kurundkar et al. · Science Translational Medicine · 2014 · 692 citations

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