Concepedia

Lactic acid induces lactate transport and glycolysis/OXPHOS interconversion in glioblastoma

Ke Duan, Zhong‐Jian Liu, Su-qiong Hu, Hong‐Yu Huo, Zhiru Xu, Jian-fei Ruan, Yang Sun, Li-ping Dai, Chang-bao Yan, Wei Xiong,

Biochemical and Biophysical Research Communications · 2018 · 75 citations · 15 references

DOI

Concepts

References

15

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.3K citations

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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Jung‐whan Kim, Irina Tchernyshyov, Gregg L. Semenza et al. · Cell Metabolism · 2006 · 3.9K citations · Full text

, , +17

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

Ioanna Papandreou, Rob A. Cairns, Lucrezia Fontana et al. · Cell Metabolism · 2006 · 2.2K citations · Full text

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Glucose feeds the TCA cycle via circulating lactate

Sheng Hui, Jonathan M. Ghergurovich, Raphael J. Morscher et al. · Nature · 2017 · 1.7K citations

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HIF-1 Inhibits Mitochondrial Biogenesis and Cellular Respiration in VHL-Deficient Renal Cell Carcinoma by Repression of C-MYC Activity

Huafeng Zhang, Ping Gao, Ryo Fukuda et al. · Cancer Cell · 2007 · 878 citations · Full text

, , +17