Stem Cell Reports · 2018 · 49 citations · 43 references
Life SciencesCell BiologyDevelopmental BiologyCell DifferentiationCell Fate SpecificationStem Cell BiologyCell Lineage SpecificationEmbryonic Stem CellsHematopoietic DevelopmentHematopoietic DifferentiationHematopoietic Stem Cell BiologyStem Cell DifferentiationEndothelial DifferentiationEndothelial-to-hematopoietic TransitionGata2 DeficiencyHematopoietic Lineage SpecificationHematopoietic Stem Cell DevelopmentHematopoietic Stem Cell DifferentiationHemogenic EndotheliumLineage Specification
non-arterial lineages. However, GATA2 is primarily needed for HE to undergo EHT. Forced expression of GATA2 in non-HE failed to induce blood formation. The lack of GATA2 requirement for generation of HE and non-HE indicates the critical role of GATA2-independent pathways in specification of these two distinct endothelial lineages.
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Chemically defined conditions for human iPSC derivation and culture
Guokai Chen, Daniel R. Gulbranson, Zhonggang Hou et al. · Nature Methods · 2011 · 1.5K citations · Full text
An early haematopoietic defect in mice lacking the transcription factor GATA-2
Fong‐Ying Tsai, Gordon Keller, Frank C. Kuo et al. · Nature · 1994 · 1.4K citations
<i>Cbfa2</i> is required for the formation of intra-aortic hematopoietic clusters
Trista E. North, Ting‐Lei Gu, Terryl Stacy et al. · Development · 1999 · 652 citations