Concepedia

Gata2 Deficiency

GATA2 Deficiency is a rare inherited bone marrow failure syndrome characterized by haploinsufficiency of the GATA2 transcription factor, leading to impaired hematopoiesis, immunodeficiency, and increased risk of myelodysplastic syndrome and acute myeloid leukemia.

122

Publications

11.5K

Citations

1.2K

Authors

434

Institutions

Publications per year

2017–2026

62

Variants

Gata2 Deficiency Syndrome

Parents

Publications

122

An early haematopoietic defect in mice lacking the transcription factor GATA-2

Fong‐Ying Tsai, Gordon Keller, Frank C. Kuo et al. · Nature · 1994 · 1.4K citations

, , +10

GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity

Michael A. Spinner, Lauren A. Sanchez, Amy P. Hsu et al. · Blood · 2013 · 706 citations · Full text

, , +12

Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome

Amy P. Hsu, Elizabeth P. Sampaio, Javed Khan et al. · Blood · 2011 · 636 citations

, , +12

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

Christopher N Hahn, Chan‐Eng Chong, Catherine Carmichael et al. · Nature Genetics · 2011 · 601 citations · Full text

, , +16

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

Pia Østergaard, Michael A. Simpson, Fiona Connell et al. · Nature Genetics · 2011 · 503 citations

, , +10

1–5 of 122

Authors

1.2K

  1. SM
    Steven M. Holland

    National Institute of Allergy and Infectious Diseases, United States

    27 publications · 3.5K citations

    22

    h-index

  2. AP
    Amy P. Hsu

    National Institute of Allergy and Infectious Diseases, United States

    25 publications · 3.3K citations

    21

    h-index

  3. DD
    Dennis D. Hickstein

    National Cancer Institute, United States

    19 publications · 2.9K citations

    17

    h-index

  4. KR
    Katherine R. Calvo

    National Institutes of Health Clinical Center, United States

    15 publications · 2.4K citations

    14

    h-index

  5. CS
    Christa S. Zerbe

    National Institute of Allergy and Infectious Diseases, United States

    11 publications · 2.4K citations

    11

    h-index

1–5 of 1.2K

Institutions

434

  1. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    23 h-index

    104 publications

    17.6K citations

  2. National Institutes of Health

    Bethesda, United States

    20 h-index

    144 publications

    17.8K citations

  3. National Cancer Institute

    Bethesda, United States

    17 h-index

    70 publications

    7.9K citations

  4. National Institutes of Health Clinical Center

    Bethesda, United States

    13 h-index

    23 publications

    2.7K citations

  5. National Heart Lung and Blood Institute

    Bethesda, United States

    9 h-index

    46 publications

    1.9K citations

  6. Center for Cancer Research

    Bethesda, United States

    9 h-index

    30 publications

    1.8K citations

  7. University of Freiburg

    Freiburg im Breisgau, Germany

    9 h-index

    57 publications

    4.8K citations

  8. Newcastle University

    Newcastle upon Tyne, United Kingdom

    8 h-index

    32 publications

    7K citations

1–8 of 434

Venues

  1. Blood

    21 publications · 4K citations

    17

    h-index

  2. Blood Advances

    10 publications · 289 citations

    10

    h-index

  3. Haematologica

    5 publications · 434 citations

    5

    h-index

  4. British Journal of Haematology

    BJH · 4 publications · 154 citations

    4

    h-index

  5. Journal of Clinical Investigation

    JCI · 4 publications · 416 citations

    4

    h-index

1–5